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Structure paper

TitleContribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis.
Journal, issue, pagesJ. Virol., Vol. 92, Year 2018
Publish dateJun 21, 2018 (structure data deposition date)
Authorsde la Higuera, I. / Ferrer-Orta, C. / Moreno, E. / de Avila, A.I. / Soria, M.E. / Singh, K. / Caridi, F. / Sobrino, F. / Sarafianos, S.G. / Perales, C. ...de la Higuera, I. / Ferrer-Orta, C. / Moreno, E. / de Avila, A.I. / Soria, M.E. / Singh, K. / Caridi, F. / Sobrino, F. / Sarafianos, S.G. / Perales, C. / Verdaguer, N. / Domingo, E.
External linksJ. Virol. / PubMed:30068642
MethodsX-ray diffraction
Resolution2.2 - 2.35 Å
Structure data

PDB-6gvv:
Mutant M16A of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

PDB-6gvy:
Mutant M16A of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with an template -primer RNA
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • foot-and-mouth disease virus - type c
  • synthetic construct (others)
KeywordsVIRAL PROTEIN / RNA dependent RNA polymerase / Picornavirus / closed right hand conformation

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