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TitleAn Aspartate-Specific Solute-Binding Protein Regulates Protein Kinase G Activity To Control Glutamate Metabolism in Mycobacteria.
Journal, issue, pagesMBio, Vol. 9, Year 2018
Publish dateJul 12, 2018 (structure data deposition date)
AuthorsBhattacharyya, N. / Nkumama, I.N. / Newland-Smith, Z. / Lin, L.Y. / Yin, W. / Cullen, R.E. / Griffiths, J.S. / Jarvis, A.R. / Price, M.J. / Chong, P.Y. ...Bhattacharyya, N. / Nkumama, I.N. / Newland-Smith, Z. / Lin, L.Y. / Yin, W. / Cullen, R.E. / Griffiths, J.S. / Jarvis, A.R. / Price, M.J. / Chong, P.Y. / Wallis, R. / O'Hare, H.M.
External linksMBio / PubMed:30065086
MethodsX-ray diffraction
Resolution1.4 - 1.68 Å
Structure data

PDB-6h1u:
GlnH bound to Asp, Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION / Resolution: 1.68 Å

PDB-6h20:
GlnH bound to Asn, Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-6h2t:
GlnH bound to Glu, Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION / Resolution: 1.67 Å

Chemicals

ChemComp-ASP:
ASPARTIC ACID

ChemComp-HOH:
WATER

ChemComp-ASN:
ASPARAGINE

ChemComp-GLU:
GLUTAMIC ACID

Source
  • mycobacterium tuberculosis (strain atcc 25618 / h37rv) (bacteria)
  • mycobacterium tuberculosis h37rv (bacteria)
KeywordsSIGNALING PROTEIN / Solute-binding protein / amino acid binding / transport / serine threonine protein kinase

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