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Structure paper

TitleStructural insights into SorCS2-Nerve Growth Factor complex formation.
Journal, issue, pagesNat Commun, Vol. 9, Page 2979-2979, Year 2018
Publish dateJan 9, 2018 (structure data deposition date)
AuthorsLeloup, N. / Chataigner, L.M.P. / Janssen, B.J.C.
External linksNat Commun / PubMed:30061605
MethodsX-ray diffraction
Resolution3.9 - 4.2 Å
Structure data

PDB-6ffy:
Structure of the mouse SorCS2-NGF complex
Method: X-RAY DIFFRACTION / Resolution: 3.9 Å

PDB-6fg9:
Mouse SORCS2 ectodomain (sortilin related VPS10 domain containing receptor 2)
Method: X-RAY DIFFRACTION / Resolution: 4.2 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • mus musculus (house mouse)
KeywordsAPOPTOSIS / SorCS2 / proNGF / p75NTR / VPS10 / Sortilin / neuroplasticity / transport / sorting

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