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TitleUnified mechanisms for self-RNA recognition by RIG-I Singleton-Merten syndrome variants.
Journal, issue, pagesElife, Vol. 7, Year 2018
Publish dateJun 5, 2018 (structure data deposition date)
AuthorsLassig, C. / Lammens, K. / Gorenflos Lopez, J.L. / Michalski, S. / Fettscher, O. / Hopfner, K.P.
External linksElife / PubMed:30047865
MethodsX-ray diffraction
Resolution2.894 Å
Structure data

PDB-6gpg:
Structure of the RIG-I Singleton-Merten syndrome variant C268F
Method: X-RAY DIFFRACTION / Resolution: 2.894 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsANTIVIRAL PROTEIN / innate immune system / RIG-I / Singleton-Merten syndrome / RNA-dependent ATPase / RNA binding protein

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