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TitleA substrate selected by phage display exhibits enhanced side-chain hydrogen bonding to HIV-1 protease.
Journal, issue, pagesActa Crystallogr D Struct Biol, Vol. 74, Page 690-694, Year 2018
Publish dateNov 30, 2017 (structure data deposition date)
AuthorsWindsor, I.W. / Raines, R.T.
External linksActa Crystallogr D Struct Biol / PubMed:29968678
MethodsX-ray diffraction
Resolution1.111 Å
Structure data

PDB-6bra:
HIV-1 protease (D25N, inactive) in complex with phage display optimized substrate SGIFLETS
Method: X-RAY DIFFRACTION / Resolution: 1.111 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus 1
  • enterobacteria phage fd (virus)
KeywordsVIRAL PROTEIN / HIV / HIV-1 / substrate / complex / phage display / recongition / hydrogen bonding

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