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Structure paper

TitleStructural insights into lethal contractural syndrome type 3 (LCCS3) caused by a missense mutation of PIP5K gamma.
Journal, issue, pagesBiochem. J., Vol. 475, Page 2257-2269, Year 2018
Publish dateMar 6, 2018 (structure data deposition date)
AuthorsZeng, X. / Uyar, A. / Sui, D. / Donyapour, N. / Wu, D. / Dickson, A. / Hu, J.
External linksBiochem. J. / PubMed:29959184
MethodsX-ray diffraction
Resolution3.102 - 3.351 Å
Structure data

PDB-6cmw:
Crystal structure of zebrafish Phosphatidylinositol-4-phosphate 5- kinase alpha isoform with bound ATP/Ca2+
Method: X-RAY DIFFRACTION / Resolution: 3.15 Å

PDB-6cn2:
Crystal structure of zebrafish Phosphatidylinositol-4-phosphate 5- kinase alpha isoform D236N with bound ATP/Ca2+
Method: X-RAY DIFFRACTION / Resolution: 3.102 Å

PDB-6cn3:
Crystal structure of zebrafish Phosphatidylinositol-4-phosphate 5- kinase alpha isoform D236A
Method: X-RAY DIFFRACTION / Resolution: 3.351 Å

Chemicals

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • danio rerio (zebrafish)
KeywordsTRANSFERASE / ATP / PIP5ka / D236N / D236A

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