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TitleTyrosine Sulfation Restricts the Conformational Ensemble of a Flexible Peptide, Strengthening the Binding Affinity for an Antibody
Journal, issue, pagesBiochemistry, Vol. 57, Page 4177-4185, Year 2018
Publish dateDec 7, 2017 (structure data deposition date)
AuthorsMiyanabe, K. / Yamashita, T. / Abe, Y. / Akiba, H. / Takamatsu, Y. / Nakakido, M. / Hamakubo, T. / Ueda, T. / Caaveiro, J.M.M. / Tsumoto, K.
External linksBiochemistry / PubMed:29936828
MethodsX-ray diffraction
Resolution1.59 Å
Structure data

PDB-5yy4:
Crystal structure of the scFv antibody 4B08 with sulfated epitope peptide
Method: X-RAY DIFFRACTION / Resolution: 1.59 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Antibody / Biomolecular recognition / MD simulations / Thermodynamics

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