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Structure paper

TitleStructural basis of meiotic chromosome synapsis through SYCP1 self-assembly.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 25, Page 557-569, Year 2018
Publish dateDec 4, 2017 (structure data deposition date)
AuthorsDunce, J.M. / Dunne, O.M. / Ratcliff, M. / Millan, C. / Madgwick, S. / Uson, I. / Davies, O.R.
External linksNat. Struct. Mol. Biol. / PubMed:29915389
MethodsX-ray diffraction
Resolution1.91 - 2.493 Å
Structure data

PDB-6f5x:
Crystal structure of the SYCP1 N-terminal head-to-head assembly in closed conformation
Method: X-RAY DIFFRACTION / Resolution: 1.91 Å

PDB-6f62:
Crystal structure of the SYCP1 N-terminal head-to-head assembly in open conformation
Method: X-RAY DIFFRACTION / Resolution: 2.066 Å

PDB-6f63:
Crystal structure of the SYCP1 C-terminal back-to-back assembly
Method: X-RAY DIFFRACTION / Resolution: 2.154 Å

PDB-6f64:
Crystal structure of the SYCP1 C-terminal back-to-back assembly
Method: X-RAY DIFFRACTION / Resolution: 2.493 Å

Chemicals

ChemComp-IOD:
IODIDE ION

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-ACT:
ACETATE ION

Source
  • homo sapiens (human)
KeywordsSTRUCTURAL PROTEIN / Meiosis / Chromosome structure / Coiled-coil / Self-assembly

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