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Structure paper

TitleStructure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer.
Journal, issue, pagesProc. Natl. Acad. Sci. U.S.A., Vol. 115, Page 7028-7032, Year 2018
Publish dateNov 30, 2017 (structure data deposition date)
AuthorsPathak, P.K. / Peng, S. / Meng, X. / Han, Y. / Zhang, B. / Zhang, F. / Xiang, Y. / Deng, J.
External linksProc. Natl. Acad. Sci. U.S.A. / PubMed:29915071
MethodsX-ray diffraction
Resolution1.6 - 2.3 Å
Structure data

PDB-6br8:
Structure of A6 reveals a novel lipid transporter
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-6br9:
Structure of A6 reveals a novel lipid transporter
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-6cb6:
CRYSTAL STRUCTURE OF VACCINIA VIRUS A6 N-TERMINUS (SPACE GROUP C2)
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-6cb7:
CRYSTAL STRUCTURE OF VACCINIA VIRUS A6 N-TERMINUS (SPACE GROUP C2)
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-6OU:
[(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate / phospholipid*YM

ChemComp-PGV:
(1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE / phospholipid*YM

ChemComp-HOH:
WATER

ChemComp-NI:
NICKEL (II) ION

Source
  • fowlpox virus (strain nvsl)
  • vaccinia virus (strain copenhagen)
KeywordsVIRAL PROTEIN / poxvirus / A6 / lipid binding / membrane biogenesis / LIPID BINDING PROTEIN / VACCINIA VIRUS / POXVIRUSES / VIRION CORE PROTEIN / VIRION MORPHOGENESIS

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