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| Title | Crystal structures of the disease-causing D444V mutant and the relevant wild type human dihydrolipoamide dehydrogenase. |
|---|---|
| Journal, issue, pages | Free Radic. Biol. Med., Vol. 124, Page 214-220, Year 2018 |
| Publish date | Apr 4, 2016 (structure data deposition date) |
Authors | Szabo, E. / Mizsei, R. / Wilk, P. / Zambo, Z. / Torocsik, B. / Weiss, M.S. / Adam-Vizi, V. / Ambrus, A. |
External links | Free Radic. Biol. Med. / PubMed:29908278 |
| Methods | X-ray diffraction |
| Resolution | 1.84 - 2.27 Å |
| Structure data | ![]() PDB-5j5z: ![]() PDB-5nhg: |
| Chemicals | ![]() ChemComp-FAD: ![]() ChemComp-PO4: ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-TRS: ![]() ChemComp-BTB: |
| Source |
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Keywords | OXIDOREDUCTASE / dihydrolipoamide dehydrogenase / E3 subunit / disease-causing mutant / E3 deficiency / pyruvate dehydrogenase complex / alpha-ketoglutarate dehydrogenase complex |
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