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-Structure paper
Title | Interdomain Stabilization Impairs CD4 Binding and Improves Immunogenicity of the HIV-1 Envelope Trimer. |
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Journal, issue, pages | Cell Host Microbe, Vol. 23, Page 832-844.e6, Year 2018 |
Publish date | May 11, 2018 (structure data deposition date) |
Authors | Zhang, P. / Gorman, J. / Geng, H. / Liu, Q. / Lin, Y. / Tsybovsky, Y. / Go, E.P. / Dey, B. / Andine, T. / Kwon, A. ...Zhang, P. / Gorman, J. / Geng, H. / Liu, Q. / Lin, Y. / Tsybovsky, Y. / Go, E.P. / Dey, B. / Andine, T. / Kwon, A. / Patel, M. / Gururani, D. / Uddin, F. / Guzzo, C. / Cimbro, R. / Miao, H. / McKee, K. / Chuang, G.Y. / Martin, L. / Sironi, F. / Malnati, M.S. / Desaire, H. / Berger, E.A. / Mascola, J.R. / Dolan, M.A. / Kwong, P.D. / Lusso, P. |
External links | Cell Host Microbe / PubMed:29902444 |
Methods | X-ray diffraction |
Resolution | 4.123 Å |
Structure data | PDB-6de7: |
Chemicals | ChemComp-NAG: ChemComp-SO4: |
Source |
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Keywords | IMMUNE SYSTEM / HIV-1 / SOSIP / Disulfide / Trimer |