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Structure paper

TitleProtein Engineering Allows for Mild Affinity-based Elution of Therapeutic Antibodies.
Journal, issue, pagesJ. Mol. Biol., Vol. 430, Page 3427-3438, Year 2018
Publish dateJan 11, 2018 (structure data deposition date)
AuthorsKanje, S. / Venskutonyte, R. / Scheffel, J. / Nilvebrant, J. / Lindkvist-Petersson, K. / Hober, S.
External linksJ. Mol. Biol. / PubMed:29886013
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-6fgo:
Fc in complex with engineered calcium binding domain Z
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-GOL:
GLYCEROL

ChemComp-CA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • staphylococcus aureus (bacteria)
KeywordsIMMUNE SYSTEM / Antibody / Protein A / EF-hand / calcium-binding

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