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Structure paper

TitleStructures of two aptamers with differing ligand specificity reveal ruggedness in the functional landscape of RNA.
Journal, issue, pagesElife, Vol. 7, Year 2018
Publish dateFeb 27, 2018 (structure data deposition date)
AuthorsKnappenberger, A.J. / Reiss, C.W. / Strobel, S.A.
External linksElife / PubMed:29877798
MethodsX-ray diffraction
Resolution2.49 - 3.097 Å
Structure data

PDB-6ck4:
G96A mutant of the PRPP riboswitch from T. mathranii bound to ppGpp
Method: X-RAY DIFFRACTION / Resolution: 3.097 Å

PDB-6ck5:
PRPP riboswitch from T. mathranii bound to PRPP
Method: X-RAY DIFFRACTION / Resolution: 2.49 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-G4P:
GUANOSINE-5',3'-TETRAPHOSPHATE

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-HOH:
WATER

ChemComp-BA:
Unknown entry

ChemComp-PRP:
1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose

Source
  • thermoanaerobacter mathranii (bacteria)
KeywordsRNA / Riboswitch / ykkC / PRPP / ppGpp

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