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Structure paper

TitleCrystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.
Journal, issue, pagesData Brief, Vol. 17, Page 356-362, Year 2018
Publish dateOct 20, 2017 (structure data deposition date)
AuthorsChen, Z. / Gutowski, S. / Sternweis, P.C.
External linksData Brief / PubMed:29876405
MethodsX-ray diffraction
Resolution1.401 - 1.995 Å
Structure data

PDB-6bca:
A Complex between PH Domain of LbcRhoGEF (AKAP-Lbc) and Activated RhoA Bound to a GTP Analog
Method: X-RAY DIFFRACTION / Resolution: 1.995 Å

PDB-6bcb:
A Complex between PH Domain of p114RhoGEF and Activated RhoA Bound to a GTP Analog
Method: X-RAY DIFFRACTION / Resolution: 1.401 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-GSP:
5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsSIGNALING PROTEIN / Rho GTPase Guanine Nucleotide Exchange Factors RhoGEF Pleckstrin Homology PH domain

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