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TitleTargeting the potent Beclin 1-UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking.
Journal, issue, pagesProc. Natl. Acad. Sci. U.S.A., Vol. 115, Page E5669-E5678, Year 2018
Publish dateNov 8, 2017 (structure data deposition date)
AuthorsWu, S. / He, Y. / Qiu, X. / Yang, W. / Liu, W. / Li, X. / Li, Y. / Shen, H.M. / Wang, R. / Yue, Z. / Zhao, Y.
External linksProc. Natl. Acad. Sci. U.S.A. / PubMed:29866835
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-5yr0:
Structure of Beclin1-UVRAG coiled coil domain complex
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsENDOCYTOSIS / autophagy regulator

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