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TitleIP6 is an HIV pocket factor that prevents capsid collapse and promotes DNA synthesis.
Journal, issue, pagesElife, Vol. 7, Year 2018
Publish dateOct 19, 2017 (structure data deposition date)
AuthorsMallery, D.L. / Marquez, C.L. / McEwan, W.A. / Dickson, C.F. / Jacques, D.A. / Anandapadamanaban, M. / Bichel, K. / Towers, G.J. / Saiardi, A. / Bocking, T. / James, L.C.
External linksElife / PubMed:29848441
MethodsX-ray diffraction
Resolution1.9 - 2 Å
Structure data

PDB-6es8:
HIV capsid hexamer with IP6 ligand
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-6h09:
HIV capsid hexamer with IP6 ligand
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-IHP:
INOSITOL HEXAKISPHOSPHATE

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus 1
  • human immunodeficiency virus type 1 group m subtype b
KeywordsVIRAL PROTEIN / HIV

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