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TitleCrystallography Coupled with Kinetic Analysis Provides Mechanistic Underpinnings of a Nicotine-Degrading Enzyme.
Journal, issue, pagesBiochemistry, Vol. 57, Page 3741-3751, Year 2018
Publish dateJan 19, 2018 (structure data deposition date)
AuthorsTararina, M.A. / Xue, S. / Smith, L.C. / Muellers, S.N. / Miranda, P.O. / Janda, K.D. / Allen, K.N.
External linksBiochemistry / PubMed:29812904
MethodsX-ray diffraction
Resolution2.649 Å
Structure data

PDB-6c71:
Nicotine Oxidoreductase in Complex with S-nicotine
Method: X-RAY DIFFRACTION / Resolution: 2.649 Å

Chemicals

ChemComp-NCT:
(S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE / alkaloid*YM

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-HOH:
WATER

Source
  • pseudomonas putida (strain s16) (bacteria)
KeywordsFLAVOPROTEIN / Monoamine oxidase family / Nicotine / Substrate specificity

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