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Structure paper

TitleStructural basis for ADP-dependent glucokinase inhibition by 8-bromo-substituted adenosine nucleotide.
Journal, issue, pagesJ. Biol. Chem., Vol. 293, Page 11088-11099, Year 2018
Publish dateMay 16, 2017 (structure data deposition date)
AuthorsGrudnik, P. / Kaminski, M.M. / Rembacz, K.P. / Kuska, K. / Madej, M. / Potempa, J. / Dawidowski, M. / Dubin, G.
External linksJ. Biol. Chem. / PubMed:29784881
MethodsX-ray diffraction
Resolution1.81 - 2 Å
Structure data

PDB-5o0i:
ADP-dependent glucokinase from Pyrococcus horikoshii
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-5o0j:
ADP-dependent glucokinase from Pyrococcus horikoshii
Method: X-RAY DIFFRACTION / Resolution: 1.81 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

ChemComp-8BR:
8-BROMO-ADENOSINE-5'-MONOPHOSPHATE

ChemComp-GLC:
alpha-D-glucopyranose

Source
  • pyrococcus horikoshii (strain atcc 700860 / dsm 12428 / jcm 9974 / nbrc 100139 / ot-3) (archaea)
KeywordsTRANSFERASE / ADP-dependent glucokinase

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