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TitleEngineering the "Missing Link" in Biosynthetic (-)-Menthol Production: Bacterial Isopulegone Isomerase.
Journal, issue, pagesACS Catal, Vol. 8, Page 2012-2020, Year 2018
Publish dateNov 30, 2017 (structure data deposition date)
AuthorsCurrin, A. / Dunstan, M.S. / Johannissen, L.O. / Hollywood, K.A. / Vinaixa, M. / Jervis, A.J. / Swainston, N. / Rattray, N.J.W. / Gardiner, J.M. / Kell, D.B. ...Currin, A. / Dunstan, M.S. / Johannissen, L.O. / Hollywood, K.A. / Vinaixa, M. / Jervis, A.J. / Swainston, N. / Rattray, N.J.W. / Gardiner, J.M. / Kell, D.B. / Takano, E. / Toogood, H.S. / Scrutton, N.S.
External linksACS Catal / PubMed:29750129
MethodsX-ray diffraction
Resolution1.08 - 2 Å
Structure data

PDB-6f4y:
CRYSTAL STRUCTURE OF KETOSTEROID ISOMERASE VARIANT D103S
Method: X-RAY DIFFRACTION / Resolution: 1.92 Å

PDB-6f50:
CRYSTAL STRUCTURE OF KETOSTEROID ISOMERASE DOUBLE VARIANT V88I/L99V
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-6f53:
CRYSTAL STRUCTURE OF KETOSTEROID ISOMERASE QUADRUPLE VARIANT V88I/L99V/D103S/V101A
Method: X-RAY DIFFRACTION / Resolution: 1.49 Å

PDB-6f54:
CRYSTAL STRUCTURE OF KETOSTEROID ISOMERASE TRIPLE VARIANT V88I/L99VD103S
Method: X-RAY DIFFRACTION / Resolution: 1.08 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • pseudomonas putida (bacteria)
KeywordsISOMERASE / Ksi

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