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| Title | Design, synthesis and evaluation of potent and selective inhibitors of mono-(ADP-ribosyl)transferases PARP10 and PARP14. |
|---|---|
| Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 28, Page 2050-2054, Year 2018 |
| Publish date | Mar 20, 2018 (structure data deposition date) |
Authors | Holechek, J. / Lease, R. / Thorsell, A.G. / Karlberg, T. / McCadden, C. / Grant, R. / Keen, A. / Callahan, E. / Schuler, H. / Ferraris, D. |
External links | Bioorg. Med. Chem. Lett. / PubMed:29748053 |
| Methods | X-ray diffraction |
| Resolution | 2.34 Å |
| Structure data | ![]() PDB-6g0w: |
| Chemicals | ![]() ChemComp-EGW: ![]() ChemComp-HOH: |
| Source |
|
Keywords | TRANSFERASE / ADP-RIBOSYLATION / INHIBITOR COMPLEX / TRANSFERASE DOMAIN |
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