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Structure paper

TitleInability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses.
Journal, issue, pagesJ. Immunol., Vol. 200, Page 3993-4003, Year 2018
Publish dateJul 30, 2017 (structure data deposition date)
AuthorsRowntree, L.C. / Nguyen, T.H.O. / Halim, H. / Purcell, A.W. / Rossjohn, J. / Gras, S. / Kotsimbos, T.C. / Mifsud, N.A.
External linksJ. Immunol. / PubMed:29735483
MethodsX-ray diffraction
Resolution1.4 - 1.82 Å
Structure data

PDB-5wmn:
Crystal Structure of HLA-B7 in complex with SPI, an influenza peptide
Method: X-RAY DIFFRACTION / Resolution: 1.82 Å

PDB-5wmo:
Crystal Structure of HLA-B7 in complex with RPP, an EBV peptide
Method: X-RAY DIFFRACTION / Resolution: 1.62 Å

PDB-5wmp:
Crystal Structure of HLA-B7 in complex with TPR, a CMV peptide
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-5wmq:
Crystal Structure of HLA-B8 in complex with ELR, an Influenza A virus peptide
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-5wmr:
Crystal Structure of HLA-B8 in complex with QIK, a CMV peptide
Method: X-RAY DIFFRACTION / Resolution: 1.58 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-IOD:
IODIDE ION

ChemComp-NA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
  • unidentified influenza virus
  • epstein-barr virus strain ag876
  • cytomegalovirus
  • influenza a virus
KeywordsIMMUNE SYSTEM / HLA / viral peptide / IAV / EBV / CMV / crossreactivity / TCR / T cell / heterologous immunity

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