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Title | Two Distinct Mechanisms for C-C Desaturation by Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenases: Importance of alpha-Heteroatom Assistance. |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 140, Page 7116-7126, Year 2018 |
Publish date | May 2, 2018 (structure data deposition date) |
![]() | Dunham, N.P. / Chang, W.C. / Mitchell, A.J. / Martinie, R.J. / Zhang, B. / Bergman, J.A. / Rajakovich, L.J. / Wang, B. / Silakov, A. / Krebs, C. ...Dunham, N.P. / Chang, W.C. / Mitchell, A.J. / Martinie, R.J. / Zhang, B. / Bergman, J.A. / Rajakovich, L.J. / Wang, B. / Silakov, A. / Krebs, C. / Boal, A.K. / Bollinger, J.M. |
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Methods | X-ray diffraction |
Resolution | 1.7 - 2.1 Å |
Structure data | ![]() PDB-6daw: ![]() PDB-6dax: ![]() PDB-6daz: ![]() PDB-6db2: |
Chemicals | ![]() ChemComp-FE2: ![]() ChemComp-ARG: ![]() ChemComp-ACT: ![]() ChemComp-HOH: ![]() ChemComp-AKG: ![]() ChemComp-HRG: ![]() ChemComp-SIN: ![]() ChemComp-G3M: ![]() ChemComp-VVO: ![]() ChemComp-EDO: |
Source |
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![]() | OXIDOREDUCTASE / desaturase / oxygenase / metalloenzyme / desaturation / natural products / biosynthesis / hydroxylase / hydroxylation / viomycin |