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TitleOligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro.
Journal, issue, pagesPLoS ONE, Vol. 13, Page e0195011-e0195011, Year 2018
Publish dateMar 15, 2017 (structure data deposition date)
AuthorsLunev, S. / Butzloff, S. / Romero, A.R. / Linzke, M. / Batista, F.A. / Meissner, K.A. / Muller, I.B. / Adawy, A. / Wrenger, C. / Groves, M.R.
External linksPLoS ONE / PubMed:29694407
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-5nfr:
Crystal structure of malate dehydrogenase from Plasmodium falciparum (PfMDH)
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-CIT:
CITRIC ACID

Source
  • plasmodium falciparum (isolate 3d7) (eukaryote)
KeywordsOXIDOREDUCTASE / Malate metabolism / Dehydrogenase / Plasmodium falciparum / Oligomerisation

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