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Structure paper

TitleTau Antibody Structure Reveals a Molecular Switch Defining a Pathological Conformation of the Tau Protein.
Journal, issue, pagesSci Rep, Vol. 8, Page 6209-6209, Year 2018
Publish dateOct 16, 2017 (structure data deposition date)
AuthorsChukwu, J.E. / Pedersen, J.T. / Pedersen, L.O. / Volbracht, C. / Sigurdsson, E.M. / Kong, X.P.
External linksSci Rep / PubMed:29670132
MethodsX-ray diffraction
Resolution2.099 Å
Structure data

PDB-6bb4:
Fab/epitope complex of mouse monoclonal antibody C5.2 targeting a phospho-tau epitope.
Method: X-RAY DIFFRACTION / Resolution: 2.099 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / monoclonal antibody / fab / tau / phosphorylation state -specific antibody

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