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IF

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Structure paper

TitleNanosecond Dynamics Regulate the MIF-Induced Activity of CD74.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Year 2018
Publish dateOct 30, 2015 (structure data deposition date)
AuthorsPantouris, G. / Ho, J. / Shah, D. / Syed, M.A. / Leng, L. / Bhandari, V. / Bucala, R. / Batista, V.S. / Loria, J.P. / Lolis, E.J.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:29669180
MethodsX-ray diffraction
Resolution1.52 - 2.54 Å
Structure data

PDB-5eiz:
Crystal structure of Y99A mutant of human macrophage migration inhibitory factor
Method: X-RAY DIFFRACTION / Resolution: 1.96 Å

PDB-5uzy:
Crystal structure of N97A mutant of human macrophage migration inhibitory factor
Method: X-RAY DIFFRACTION / Resolution: 1.71 Å

PDB-6bg6:
Crystal structure of S111A mutant of human macrophage migration inhibitory factor
Method: X-RAY DIFFRACTION / Resolution: 1.52 Å

PDB-6bg7:
Crystal structure of G107A mutant of human macrophage migration inhibitory factor
Method: X-RAY DIFFRACTION / Resolution: 2.54 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-IPA:
ISOPROPYL ALCOHOL / alkaloid*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsISOMERASE / surface / mutation / trimeric

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