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TitleDevelopment of Macrocyclic Peptidomimetics Containing Constrained alpha , alpha-Dialkylated Amino Acids with Potent and Selective Activity at Human Melanocortin Receptors.
Journal, issue, pagesJ. Med. Chem., Vol. 61, Page 4263-4269, Year 2018
Publish dateDec 20, 2017 (structure data deposition date)
AuthorsMerlino, F. / Zhou, Y. / Cai, M. / Carotenuto, A. / Yousif, A.M. / Brancaccio, D. / Di Maro, S. / Zappavigna, S. / Limatola, A. / Novellino, E. ...Merlino, F. / Zhou, Y. / Cai, M. / Carotenuto, A. / Yousif, A.M. / Brancaccio, D. / Di Maro, S. / Zappavigna, S. / Limatola, A. / Novellino, E. / Grieco, P. / Hruby, V.J.
External linksJ. Med. Chem. / PubMed:29660981
MethodsNMR (solution)
Structure data

PDB-6fce:
NMR ensemble of Macrocyclic Peptidomimetic Containing Constrained a,a-dialkylated Amino Acids with Potent and Selective Activity at Human Melanocortin Receptors
Method: SOLUTION NMR

Source
  • synthetic construct (others)
KeywordsDE NOVO PROTEIN / Melanocortin / Peptidomimetics / Amino acid / dialkylated

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