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Structure paper

TitleInsights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65.
Journal, issue, pagesHum. Mol. Genet., Vol. 27, Page 2225-2243, Year 2018
Publish dateJan 22, 2018 (structure data deposition date)
AuthorsChoi, E.H. / Suh, S. / Sander, C.L. / Hernandez, C.J.O. / Bulman, E.R. / Khadka, N. / Dong, Z. / Shi, W. / Palczewski, K. / Kiser, P.D.
External linksHum. Mol. Genet. / PubMed:29659842
MethodsX-ray diffraction
Resolution2.5 - 3.15 Å
Structure data

PDB-6c7k:
Crystal structure of an ACO/RPE65 chimera
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-6c7o:
Crystal structure of D477G ACO/RPE65 chimera, trigonal crystal form
Method: X-RAY DIFFRACTION / Resolution: 3.15 Å

PDB-6c7p:
Crystal structure of D477G ACO/RPE65 chimera, monoclinic crystal form
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-FE2:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • synechocystis sp. (strain pcc 6803 / kazusa) (bacteria)
KeywordsOXIDOREDUCTASE / non-heme iron / chimera / 7-bladed propeller / dominant mutation

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