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| Title | The Crystal Structure of the R280K Mutant of Human p53 Explains the Loss of DNA Binding. |
|---|---|
| Journal, issue, pages | Int J Mol Sci, Vol. 19, Year 2018 |
| Publish date | Jan 4, 2018 (structure data deposition date) |
Authors | Gomes, A.S. / Trovao, F. / Andrade Pinheiro, B. / Freire, F. / Gomes, S. / Oliveira, C. / Domingues, L. / Romao, M.J. / Saraiva, L. / Carvalho, A.L. |
External links | Int J Mol Sci / PubMed:29652801 |
| Methods | X-ray diffraction |
| Resolution | 2 Å |
| Structure data | ![]() PDB-6ff9: |
| Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-HOH: |
| Source |
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Keywords | DNA BINDING PROTEIN / p53 / mutant / DNA binding / anticancer therapy |
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