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TitleTreating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement.
Journal, issue, pagesNat Commun, Vol. 9, Page 1421-1421, Year 2018
Publish dateMay 25, 2017 (structure data deposition date)
AuthorsOrengo, J.M. / Radin, A.R. / Kamat, V. / Badithe, A. / Ben, L.H. / Bennett, B.L. / Zhong, S. / Birchard, D. / Limnander, A. / Rafique, A. ...Orengo, J.M. / Radin, A.R. / Kamat, V. / Badithe, A. / Ben, L.H. / Bennett, B.L. / Zhong, S. / Birchard, D. / Limnander, A. / Rafique, A. / Bautista, J. / Kostic, A. / Newell, D. / Duan, X. / Franklin, M.C. / Olson, W. / Huang, T. / Gandhi, N.A. / Lipsich, L. / Stahl, N. / Papadopoulos, N.J. / Murphy, A.J. / Yancopoulos, G.D.
External linksNat Commun / PubMed:29650949
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-5vyf:
Structure of single chain Fel d 1 bound to a neutralizing antibody
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • felis catus (domestic cat)
KeywordsIMMUNE SYSTEM / antibody / allergen / therapeutic

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