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Structure paper

TitleStructural plasticity of the TDRD3 Tudor domain probed by a fragment screening hit.
Journal, issue, pagesFEBS J., Vol. 285, Page 2091-2103, Year 2018
Publish dateOct 9, 2017 (structure data deposition date)
AuthorsLiu, J. / Zhang, S. / Liu, M. / Liu, Y. / Nshogoza, G. / Gao, J. / Ma, R. / Yang, Y. / Wu, J. / Zhang, J. ...Liu, J. / Zhang, S. / Liu, M. / Liu, Y. / Nshogoza, G. / Gao, J. / Ma, R. / Yang, Y. / Wu, J. / Zhang, J. / Li, F. / Ruan, K.
External linksFEBS J. / PubMed:29645362
MethodsX-ray diffraction
Resolution1.762 Å
Structure data

PDB-5yj8:
Identification of a small molecule inhibitor for the Tudor domain of TDRD3
Method: X-RAY DIFFRACTION / Resolution: 1.762 Å

Chemicals

ChemComp-8W9:
5-(aminomethyl)-1,3-dimethyl-benzimidazol-2-one

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION/INHIBITOR / Transcriptional coactivator / complex / inhibitor / TRANSCRIPTION-INHIBITOR complex

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