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TitleTargeting IS608 transposon integration to highly specific sequences by structure-based transposon engineering.
Journal, issue, pagesNucleic Acids Res., Vol. 46, Page 4152-4163, Year 2018
Publish dateJan 17, 2018 (structure data deposition date)
AuthorsMorero, N.R. / Zuliani, C. / Kumar, B. / Bebel, A. / Okamoto, S. / Guynet, C. / Hickman, A.B. / Chandler, M. / Dyda, F. / Barabas, O.
External linksNucleic Acids Res. / PubMed:29635476
MethodsX-ray diffraction
Resolution2.598 Å
Structure data

PDB-6fi8:
Crystal structure of the IS608 transposase in complex with left end 29-mer DNA hairpin and a 6-mer DNA representing the intact target site: pre-cleavage target capture complex
Method: X-RAY DIFFRACTION / Resolution: 2.598 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • helicobacter pylori (bacteria)
KeywordsDNA BINDING PROTEIN / DNA-BINDING PROTEIN / PROTEIN-DNA COMPLEX / HUH MOTIF / DNA STEM LOOP / Transposition / TnpA transposase / target capture complex / ISHp608

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