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TitleCrystal structures of FMN-bound and FMN-free forms of dihydroorotate dehydrogenase fromTrypanosoma brucei.
Journal, issue, pagesFEBS Open Bio, Vol. 8, Page 680-691, Year 2018
Publish dateApr 11, 2017 (structure data deposition date)
AuthorsKubota, T. / Tani, O. / Yamaguchi, T. / Namatame, I. / Sakashita, H. / Furukawa, K. / Yamasaki, K.
External linksFEBS Open Bio / PubMed:29632820
MethodsX-ray diffraction
Resolution1.6 - 1.79 Å
Structure data

PDB-5xfv:
Crystal structures of FMN-bound form of dihydroorotate dehydrogenase from Trypanosoma brucei
Method: X-RAY DIFFRACTION / Resolution: 1.79 Å

PDB-5xfw:
Crystal structures of FMN-free form of dihydroorotate dehydrogenase from Trypanosoma brucei
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-MLI:
MALONATE ION

ChemComp-HOH:
WATER

Source
  • trypanosoma brucei brucei strain 927/4 gutat10.1 (eukaryote)
  • trypanosoma brucei brucei (strain 927/4 gutat10.1) (eukaryote)
KeywordsOXIDOREDUCTASE / Neglected Tropical Diseases Flavin Enzyme Pyrimidine metabolism

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