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Structure paper

TitleDisease-Causing Mutations in the G Protein G alpha s Subvert the Roles of GDP and GTP.
Journal, issue, pagesCell, Vol. 173, Page 1254-1264.e11, Year 2018
Publish dateAug 30, 2017 (structure data deposition date)
AuthorsHu, Q. / Shokat, K.M.
External linksCell / PubMed:29628140
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-6au6:
Crystal structure of GDP-bound human GNAS R201C mutant
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / G protein / GDP / active conformation

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