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Structure paper

TitleRescue of conformational dynamics in enzyme catalysis by directed evolution.
Journal, issue, pagesNat Commun, Vol. 9, Page 1314-1314, Year 2018
Publish dateJun 29, 2017 (structure data deposition date)
AuthorsOtten, R. / Liu, L. / Kenner, L.R. / Clarkson, M.W. / Mavor, D. / Tawfik, D.S. / Kern, D. / Fraser, J.S.
External linksNat Commun / PubMed:29615624
MethodsX-ray diffraction
Resolution1.43 - 1.5 Å
Structure data

PDB-5wc7:
CypA Mutant - I97V S99T C115S
Method: X-RAY DIFFRACTION / Resolution: 1.43 Å

PDB-6bta:
CypA Mutant - S99T C115S
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsISOMERASE / proline isomerase

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