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TitleDevelopment of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1.
Journal, issue, pagesJ. Med. Chem., Vol. 61, Page 3674-3684, Year 2018
Publish dateDec 13, 2017 (structure data deposition date)
AuthorsDurek, T. / Cromm, P.M. / White, A.M. / Schroeder, C.I. / Kaas, Q. / Weidmann, J. / Ahmad Fuaad, A. / Cheneval, O. / Harvey, P.J. / Daly, N.L. ...Durek, T. / Cromm, P.M. / White, A.M. / Schroeder, C.I. / Kaas, Q. / Weidmann, J. / Ahmad Fuaad, A. / Cheneval, O. / Harvey, P.J. / Daly, N.L. / Zhou, Y. / Dellsen, A. / Osterlund, T. / Larsson, N. / Knerr, L. / Bauer, U. / Kessler, H. / Cai, M. / Hruby, V.J. / Plowright, A.T. / Craik, D.J.
External linksJ. Med. Chem. / PubMed:29605997
MethodsNMR (solution)
Structure data

PDB-6bvu:
SFTI-HFRW-1
Method: SOLUTION NMR

PDB-6bvw:
SFTI-HFRW-3
Method: SOLUTION NMR

PDB-6bvx:
SFTI-HFRW-2
Method: SOLUTION NMR

PDB-6bvy:
SFTI-HFRW-4
Method: SOLUTION NMR

Source
  • helianthus annuus (common sunflower)
KeywordsBIOSYNTHETIC PROTEIN / melanocortin / pharmacophore / cyclic peptide / SFTI / grafting

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