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Structure paper

TitleStructural basis of DUX4/IGH-driven transactivation.
Journal, issue, pagesLeukemia, Vol. 32, Page 1466-1476, Year 2018
Publish dateJan 3, 2018 (structure data deposition date)
AuthorsDong, X. / Zhang, W. / Wu, H. / Huang, J. / Zhang, M. / Wang, P. / Zhang, H. / Chen, Z. / Chen, S.J. / Meng, G.
External linksLeukemia / PubMed:29572508
MethodsX-ray diffraction
Resolution1.5 - 2.623 Å
Structure data

PDB-5z2s:
Crystal structure of DUX4-HD2 domain
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-5z2t:
Crystal structure of DNA-bound DUX4-HD2
Method: X-RAY DIFFRACTION / Resolution: 2.623 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN / acute lymphoblastic leukemia / DUX4/IGH / DUX4-Responsive-Element / transactivation / ERGalt / DNA BINDING PROTEIN/DNA / DNA BINDING PROTEIN-DNA COMPLEX

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