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-Structure paper
Title | Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain |
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Journal, issue, pages | SLAS Discov, Vol. 23, Page 930-940, Year 2018 |
Publish date | Jun 2, 2017 (structure data deposition date) |
![]() | Senisterra, G. / Zhu, H.Y. / Luo, X. / Zhang, H. / Xun, G. / Lu, C. / Xiao, W. / Hajian, T. / Loppnau, P. / Chau, I. ...Senisterra, G. / Zhu, H.Y. / Luo, X. / Zhang, H. / Xun, G. / Lu, C. / Xiao, W. / Hajian, T. / Loppnau, P. / Chau, I. / Li, F. / Allali-Hassani, A. / Atadja, P. / Oyang, C. / Li, E. / Brown, P.J. / Arrowsmith, C.H. / Zhao, K. / Yu, Z. / Vedadi, M. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.2 Å |
Structure data | ![]() PDB-5xpi: |
Chemicals | ![]() ChemComp-8C3: ![]() ChemComp-HOH: |
Source |
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![]() | LIGASE / TTD domain / small molecule |