タイトル | Ligand channel in pharmacologically stabilized rhodopsin. |
---|
ジャーナル・号・ページ | Proc. Natl. Acad. Sci. U.S.A., Vol. 115, Page 3640-3645, Year 2018 |
---|
掲載日 | 2018年1月23日 (構造データの登録日) |
---|
著者 | Mattle, D. / Kuhn, B. / Aebi, J. / Bedoucha, M. / Kekilli, D. / Grozinger, N. / Alker, A. / Rudolph, M.G. / Schmid, G. / Schertler, G.F.X. ...Mattle, D. / Kuhn, B. / Aebi, J. / Bedoucha, M. / Kekilli, D. / Grozinger, N. / Alker, A. / Rudolph, M.G. / Schmid, G. / Schertler, G.F.X. / Hennig, M. / Standfuss, J. / Dawson, R.J.P. |
---|
リンク | Proc. Natl. Acad. Sci. U.S.A. / PubMed:29555765 |
---|
手法 | X線回折 |
---|
解像度 | 2.36 - 3.03 Å |
---|
構造データ | PDB-6fk6: Crystal structure of N2C/D282C stabilized opsin bound to RS01 手法: X-RAY DIFFRACTION / 解像度: 2.36 Å PDB-6fk7: Crystal structure of N2C/D282C stabilized opsin bound to RS06 手法: X-RAY DIFFRACTION / 解像度: 2.62 Å PDB-6fk8: Crystal structure of N2C/D282C stabilized opsin bound to RS08 手法: X-RAY DIFFRACTION / 解像度: 2.87 Å PDB-6fk9: Crystal structure of N2C/D282C stabilized opsin bound to RS09 手法: X-RAY DIFFRACTION / 解像度: 2.63 Å PDB-6fka: Crystal structure of N2C/D282C stabilized opsin bound to RS11 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-6fkb: Crystal structure of N2C/D282C stabilized opsin bound to RS13 手法: X-RAY DIFFRACTION / 解像度: 3.03 Å PDB-6fkc: Crystal structure of N2C/D282C stabilized opsin bound to RS15 手法: X-RAY DIFFRACTION / 解像度: 2.46 Å PDB-6fkd: Crystal structure of N2C/D282C stabilized opsin bound to RS16 手法: X-RAY DIFFRACTION / 解像度: 2.49 Å |
---|
化合物 | ChemComp-DOK: (2~{S})-2-(4-chlorophenyl)-3-methyl-1-spiro[1,3-benzodioxole-2,4'-piperidine]-1'-yl-butan-1-one
ChemComp-DO5: (2~{R},3~{R})-2-(4-chlorophenyl)-3-oxidanyl-1-spiro[1,3-benzodioxole-2,4'-piperidine]-1'-yl-butan-1-one
ChemComp-DNZ: (2~{R},3~{S})-3-azanyl-2-(4-chlorophenyl)-1-spiro[1,3-benzodioxole-2,4'-piperidine]-1'-yl-butan-1-one
ChemComp-DNK: (2~{S})-3-methyl-2-phenyl-1-spiro[1,3-benzodioxole-2,4'-piperidine]-1'-yl-butan-1-one
ChemComp-DN5: (2~{S})-2-(3,4-dichlorophenyl)-3-methyl-1-spiro[1,3-benzodioxole-2,4'-piperidine]-1'-yl-butan-1-one
ChemComp-DLH: 2-(4-chlorophenyl)-1-spiro[1,3-benzodioxole-2,4'-piperidine]-1'-yl-ethanone
ChemComp-DLB: 3-[1'-[(2~{S})-2-(4-chlorophenyl)-3-methyl-butanoyl]spiro[1,3-benzodioxole-2,4'-piperidine]-5-yl]propanoic acid
ChemComp-DL2: 5-chloranyl-2-(2-oxidanylidene-2-spiro[1,3-benzodioxole-2,4'-piperidine]-1'-yl-ethyl)-3~{H}-pyridin-6-one
|
---|
由来 | - bos taurus (ウシ)
|
---|
キーワード | MEMBRANE PROTEIN / RHODOPSIN / G PROTEIN-COUPLED RECEPTORS / RETINITIS PIGMENTOSA / SIGNALING PROTEIN / SENSORY TRANSDUCTION / PHOTORECEPTOR PROTEIN / KINTEGRAL MEMBRANE PROTEIN / VISION / MEMBRANE / RECEPTOR / TRANSDUCER PHOTORECEPTOR / SMALL MOLECULE COMPLEX |
---|