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Structure paper

TitleFactor Xa and VIIa inhibition by tissue factor pathway inhibitor is prevented by a monoclonal antibody to its Kunitz-1 domain.
Journal, issue, pagesJ. Thromb. Haemost., Vol. 16, Page 893-904, Year 2018
Publish dateApr 7, 2017 (structure data deposition date)
AuthorsAugustsson, C. / Svensson, A. / Kjaer, B. / Chao, T.Y. / Wenjuan, X. / Krogh, B.O. / Breinholt, J. / Clausen, J.T. / Hilden, I. / Petersen, H.H. / Petersen, L.C.
External linksJ. Thromb. Haemost. / PubMed:29532595
MethodsX-ray diffraction
Resolution1.65 Å
Structure data

PDB-5nmv:
Crystal structure of 2F22 Fab fragment against TFPI1
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • mus (mice)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Fab

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