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Structure paper

TitleA New Critical Conformational Determinant of Multidrug Efflux by an MFS Transporter.
Journal, issue, pagesJ. Mol. Biol., Vol. 430, Page 1368-1385, Year 2018
Publish dateOct 31, 2017 (structure data deposition date)
AuthorsZomot, E. / Yardeni, E.H. / Vargiu, A.V. / Tam, H.K. / Malloci, G. / Ramaswamy, V.K. / Perach, M. / Ruggerone, P. / Pos, K.M. / Bibi, E.
External linksJ. Mol. Biol. / PubMed:29530612
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-6euq:
MdfA(Q131R/L339E)
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-BNG:
nonyl beta-D-glucopyranoside / detergent*YM

ChemComp-DXC:
(3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID / detergent*YM

ChemComp-PR:
PRASEODYMIUM ION

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-OCT:
N-OCTANE

ChemComp-HEX:
HEXANE

ChemComp-ACT:
ACETATE ION

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • escherichia coli (strain k12) (bacteria)
KeywordsTRANSPORT PROTEIN / Multidrug efflux protein / Membrane protein

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