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Structure paper

TitleHuman IFIT3 Modulates IFIT1 RNA Binding Specificity and Protein Stability.
Journal, issue, pagesImmunity, Vol. 48, Page 487-499.e5, Year 2018
Publish dateJan 18, 2018 (structure data deposition date)
AuthorsJohnson, B. / VanBlargan, L.A. / Xu, W. / White, J.P. / Shan, C. / Shi, P.Y. / Zhang, R. / Adhikari, J. / Gross, M.L. / Leung, D.W. ...Johnson, B. / VanBlargan, L.A. / Xu, W. / White, J.P. / Shan, C. / Shi, P.Y. / Zhang, R. / Adhikari, J. / Gross, M.L. / Leung, D.W. / Diamond, M.S. / Amarasinghe, G.K.
External linksImmunity / PubMed:29525521
MethodsX-ray diffraction
Resolution2.54 Å
Structure data

PDB-6c6k:
Structural basis for preferential recognition of cap 0 RNA by a human IFIT1-IFIT3 protein complex
Method: X-RAY DIFFRACTION / Resolution: 2.54 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • equine encephalosis virus
KeywordsRNA BINDING PROTEIN/RNA / innate immunity / Interferon stimulated genes / Host defense / antiviral / self/non-self RNA recognition / pathogen associated molecular patterns / flavivirus / RNA binding protein-RNA complex

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