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TitleStructure-function analyses of a stereotypic rheumatoid factor unravel the structural basis for germline-encoded antibody autoreactivity.
Journal, issue, pagesJ. Biol. Chem., Vol. 293, Page 7008-7016, Year 2018
Publish dateMay 15, 2017 (structure data deposition date)
AuthorsShiroishi, M. / Ito, Y. / Shimokawa, K. / Lee, J.M. / Kusakabe, T. / Ueda, T.
External linksJ. Biol. Chem. / PubMed:29523691
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-5xmh:
Crystal structure of an IgM rheumatoid factor YES8c in complex with IgG1 Fc
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Immunoglobulin / Complex / Rheumatoid factor / Autoantibody

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