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Structure paper

TitleMitotic spindle association of TACC3 requires Aurora-A-dependent stabilization of a cryptic alpha-helix.
Journal, issue, pagesEMBO J., Vol. 37, Year 2018
Publish dateJul 6, 2017 (structure data deposition date)
AuthorsBurgess, S.G. / Mukherjee, M. / Sabir, S. / Joseph, N. / Gutierrez-Caballero, C. / Richards, M.W. / Huguenin-Dezot, N. / Chin, J.W. / Kennedy, E.J. / Pfuhl, M. ...Burgess, S.G. / Mukherjee, M. / Sabir, S. / Joseph, N. / Gutierrez-Caballero, C. / Richards, M.W. / Huguenin-Dezot, N. / Chin, J.W. / Kennedy, E.J. / Pfuhl, M. / Royle, S.J. / Gergely, F. / Bayliss, R.
External linksEMBO J. / PubMed:29510984
MethodsX-ray diffraction
Resolution2.021 Å
Structure data

PDB-5odt:
Aurora-A in complex with TACC3
Method: X-RAY DIFFRACTION / Resolution: 2.021 Å

Chemicals

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Mitotic kinase

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