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TitleA potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement.
Journal, issue, pagesJ. Biol. Chem., Vol. 293, Page 6269-6281, Year 2018
Publish dateSep 13, 2017 (structure data deposition date)
AuthorsJensen, R.K. / Pihl, R. / Gadeberg, T.A.F. / Jensen, J.K. / Andersen, K.R. / Thiel, S. / Laursen, N.S. / Andersen, G.R.
External linksJ. Biol. Chem. / PubMed:29497000
MethodsX-ray diffraction
Resolution2.65 Å
Structure data

PDB-6ehg:
complement component C3b in complex with a nanobody
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • lama glama (llama)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Protein Complex / Inhibitor / Complement / Complement System / single domain antibody / nanobody

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