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TitleStructural basis of the broad substrate tolerance of the antibody 7B9-catalyzed hydrolysis of p-nitrobenzyl esters.
Journal, issue, pagesBioorg. Med. Chem., Vol. 26, Page 1412-1417, Year 2018
Publish dateJun 7, 2017 (structure data deposition date)
AuthorsMiyamoto, N. / Yoshimura, M. / Okubo, Y. / Suzuki-Nagata, K. / Tsumuraya, T. / Ito, N. / Fujii, I.
External linksBioorg. Med. Chem. / PubMed:29496413
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-5xqw:
Catalytic antibody 7B9
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-8EU:
ethyl-[(4-nitrophenyl)methoxy]phosphinic acid

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / catalytic antibody / hydrolytic enzyme / Fab / transition-state analogue

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