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TitleGrouper iridovirus GIV66 is a Bcl-2 protein that inhibits apoptosis by exclusively sequestering Bim.
Journal, issue, pagesJ. Biol. Chem., Vol. 293, Page 5464-5477, Year 2018
Publish dateApr 27, 2017 (structure data deposition date)
AuthorsBanjara, S. / Mao, J. / Ryan, T.M. / Caria, S. / Kvansakul, M.
External linksJ. Biol. Chem. / PubMed:29483196
MethodsX-ray diffraction
Resolution1.65 - 1.7 Å
Structure data

PDB-5vmn:
Crystal structure of grouper iridovirus GIV66
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

PDB-5vmo:
Crystal structure of grouper iridovirus GIV66:Bim complex
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-NO3:
NITRATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

Source
  • grouper iridovirus
  • danio rerio (zebrafish)
KeywordsVIRAL PROTEIN / Apoptosis / Bcl-2 / iridovirus / grouper / VIRAL PROTEIN/apoptosis / VIRAL PROTEIN-apoptosis complex

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