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-Structure paper
Title | Identification of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase. |
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Journal, issue, pages | Biochem. Biophys. Res. Commun., Vol. 497, Page 835-842, Year 2018 |
Publish date | Dec 18, 2017 (structure data deposition date) |
Authors | Lunev, S. / Bosch, S.S. / Batista, F.A. / Wang, C. / Li, J. / Linzke, M. / Kruithof, P. / Chamoun, G. / Domling, A.S.S. / Wrenger, C. / Groves, M.R. |
External links | Biochem. Biophys. Res. Commun. / PubMed:29476738 |
Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | PDB-6fba: |
Chemicals | ChemComp-SO4: ChemComp-D48: ChemComp-DMS: ChemComp-MLI: ChemComp-GOL: ChemComp-NA: ChemComp-PEG: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / Falciparum Malaria Pyrimidine biosynthesis Trimer Hit Inhibitor |