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TitleStructural basis of sterol binding and transport by a yeast StARkin domain.
Journal, issue, pagesJ. Biol. Chem., Vol. 293, Page 5522-5531, Year 2018
Publish dateDec 20, 2017 (structure data deposition date)
AuthorsJentsch, J.A. / Kiburu, I. / Pandey, K. / Timme, M. / Ramlall, T. / Levkau, B. / Wu, J. / Eliezer, D. / Boudker, O. / Menon, A.K.
External linksJ. Biol. Chem. / PubMed:29463678
MethodsX-ray diffraction
Resolution2.195 - 2.2 Å
Structure data

PDB-6byd:
Crystal structure of the second StART domain of yeast Lam4
Method: X-RAY DIFFRACTION / Resolution: 2.195 Å

PDB-6bym:
Crystal structure of the sterol-bound second StART domain of yeast Lam4
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-HC3:
25-HYDROXYCHOLESTEROL / antivirus*YM

Source
  • saccharomyces cerevisiae (strain atcc 204508 / s288c) (yeast)
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsLIPID TRANSPORT / Sterol Transport

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