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TitleIdentification of Native and Posttranslationally Modified HLA-B*57:01-Restricted HIV Envelope Derived Epitopes Using Immunoproteomics.
Journal, issue, pagesProteomics, Vol. 18, Page e1700253-e1700253, Year 2018
Publish dateDec 18, 2017 (structure data deposition date)
AuthorsRamarathinam, S.H. / Gras, S. / Alcantara, S. / Yeung, A.W.S. / Mifsud, N.A. / Sonza, S. / Illing, P.T. / Glaros, E.N. / Center, R.J. / Thomas, S.R. ...Ramarathinam, S.H. / Gras, S. / Alcantara, S. / Yeung, A.W.S. / Mifsud, N.A. / Sonza, S. / Illing, P.T. / Glaros, E.N. / Center, R.J. / Thomas, S.R. / Kent, S.J. / Ternette, N. / Purcell, D.F.J. / Rossjohn, J. / Purcell, A.W.
External linksProteomics / PubMed:29437277
MethodsX-ray diffraction
Resolution1.45 - 1.58 Å
Structure data

PDB-6bxp:
Crystal Structure of HLA-B*57:01 with a modified HIV peptide RKV-Kyn
Method: X-RAY DIFFRACTION / Resolution: 1.45 Å

PDB-6bxq:
Crystal Structure of HLA-B*57:01 with an HIV peptide RKV
Method: X-RAY DIFFRACTION / Resolution: 1.58 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • human immunodeficiency virus 1
KeywordsIMMUNE SYSTEM / Immunopeptidome / kynurenine / HIV / PTM / HLA-B*57:01

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