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TitleHarnessing insulin- and leptin-induced oxidation of PTP1B for therapeutic development.
Journal, issue, pagesNat Commun, Vol. 9, Page 283-283, Year 2018
Publish dateApr 6, 2017 (structure data deposition date)
AuthorsKrishnan, N. / Bonham, C.A. / Rus, I.A. / Shrestha, O.K. / Gauss, C.M. / Haque, A. / Tocilj, A. / Joshua-Tor, L. / Tonks, N.K.
External linksNat Commun / PubMed:29348454
MethodsX-ray diffraction
Resolution1.635 Å
Structure data

PDB-5vf6:
Crystal structure of single chain variable fragment (scFv45).
Method: X-RAY DIFFRACTION / Resolution: 1.635 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • gallus gallus (chicken)
KeywordsIMMUNE SYSTEM / single chain variable fragment / scFv / conformation-sensor antibodies / intrabodies

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